Get Ready For The Lawsuits
Found a video that explains the effects on red blood cells that I think is extremely urgent.
Graphene oxide is known to be an ingredient in recent flu vaccines. It is also being proposed for use as an ingredient in ‘nasal’ mist flu vaccines.
The injected have much more damage and larger particles than those who just inhaled them, regardless they are still highly damaging and toxic.
Graphene is ‘blinding’ the immune system, see tolerance below. A property well known by Robert Malone and everyone else as it is used as an immune suppressant for organ transplants. You can clearly see the effects of that in the video, no white cells or macrophages are coming to do the job they would normally do to ‘phage’ dead cells. Educated guess, going to be relying on ‘chemistry’ with ability to degrade the material outside of the ‘immune’ response. Aside from the usual ‘detoxicants’ what that would be I don’t know. The secret might lie in Ivermectin which a complex synthetic (which if you saw last post is probably ‘deradiating’ but not degrading graphene although I could be wrong). Glutathione production is part of the immune system. I’ve never seen glutathione supplements that actually work (aside from colostrum) but maybe they have improved and according to the literature the combination with NAC has brought amazing improvement even in ICU. Charcoal never leaves your gut, whether is has actual ability to attract and bind this substance from the blood, I don’t know. Zeolite, I don’t know. Graphene oxide is a new chemical. If they (DOD) would spill the beans…. maybe…. but since DOD is still enforcing the usual death cocktail along with ventilation, under Operation Warp Speed, they have a different agenda (protect Israel).
Be aware – dry scaly skin is also the result of liver damage if you are ingesting other drugs and becoming toxic. This is slightly different.
I’m not an expert but I’m probably more inclined to believe the graphenes are bio accumulating toward particular areas in the body that have a greater electrical effect, the heart etc. Possibly with the help of metals to increase the magnetic effects although the video does clearly show they are growing in size. As they state in the video since the ‘companies’ are claiming this proprietary information they will not release the ingredients and thereby forcing independent review, I would simply say ask a meth dealer if he thinks he is going to keep his ‘recipe’ secret once a felony is involved. That is a ludicrous presumption regarding ‘liability’.
Regarding crowds and the ‘no choir’ rule in some countries. Remember that one? They were exhaling. I remind you a military operation that the DOD was explicitly aware of what they were dealing with as a ‘chemical intoxicant’. Please spare me the incredulity, it’s getting old.
Another receipt. We’ve got the goods.
I’ve also been checking into the Bluetooth phenomena. All codes are specifically assigned to particular electronic equipment. These are new ‘codes’ being transmitted from ‘the injected’. It doesn’t appear to be just a party trick. So if you want it, there’s an app for that and by the way since you must turn off your device when flying and in this particular case, you can’t, I wouldn’t be flying or sitting in a plane with a large group of people amplifying ‘strange’ signals.
GRAPHENE CAN BE WRITTEN ON ANYTHING FORMING CIRCUITS
2-27-22
New audio.
Bottom line, nobody wants you to be living to age 120.
You would never hit the gas and brake (cause massive apoptosis and inhibit autophagy/phagocytosis) at the same time and this is essentially what ‘this injection’ does as a bio nuclear attack on ‘cells’. Also destroying oxygen and interfering with clotting ability. Of course they know that particular (mass toxic effect).
I looked up some of these ‘new cancer drugs’ (the mechanism) after realizing what this person said they were on for cancer ‘treatment’ that sounded like they might be a Robert Malone specialty ‘autophagy inhibitors’ and I was horrified.
A leaked Pfizer document shows they destroy chromosomes and you would never want a drug that causes mass cell death while preventing your natural defense system from working.
Make sure you understand what the words Carbon Tax are applying to, warning to the ‘graphenites’, we’re not paying.
2-26-22
Even though I think it is important to avoid ‘crimes of the future’, removed history commentary. People won’t wake up until they get the boot and they’ll unwittingly force it as a protest (see Jan. 6) but not an actual labor strike (where the real power is to break the back of the oppressor). Trudeau knows this, Boris knows this, Biden knows this, that’s why the ‘pressure’ is off.
A tale of two cities.
Sasei Mirai
I’m not sure but appears Bravo® has been re-formulated.
Bravo®
ICU Intubated Covid Patients Healed Within Hours When Treated with Glutathione and NAC
Purify And The True Purpose For Determining The Shedding Factor – Not Protein Damage
It might not hurt to invest in one for your home.
One more clue, Debra Birx went on to become a major investor in ‘filtration’, gee wonder why. Because she’s a lying criminal racketeer that already did her ‘job’ that’s why (in more countries than one I might add). I would suggest the company from Stew Peters, can’t remember the name. I’m sure can be found on his website.
Isn’t it ironic, I never treated anyone as ‘contaminated’ until they actually were (was I afraid of non existent ‘virus’ or a ‘protein’, not in the least; no way would I get the death injection or any injection for that matter; meanwhile for them ‘everything’ was contaminated.
The blood of the vaccinated vs. the unvaccinated.
GRAPHENE IS BEING TRANSMITTED FROM THE “VACCINATED” TO VACCINE-FREE PEOPLE
The vaccinated are “shedding” and infecting the unvaccinated
Dr. Philippe Van Welbergen, medical director of Biomedics Clinic in the United Kingdom, recently demonstrated that the graphene in the COVID-19 vaccines is organizing and growing into large fibers and structures, gaining magnetic properties and becoming more complex.
In mid-2021, Van Welbergen first noticed a problem when he started receiving more and more patients who exhibited an unusual array of symptoms. He explained in an interview with a South African media outlet that his patients started complaining about chronic fatigue, dizziness, memory issues, paralysis and even late-onset of heavy menstruation for women in their 60s.
Van Welbergen was concerned that it may have something to do with structural changes in their blood, and so he took blood samples from all of them.
Upon examining the blood samples under a microscope, he found that their blood was clumping up and forming strange shapes not typically seen in healthy blood. The shape of individual red blood cells was also not round, but more “crumpled.”
Van Welbergen also found that the nuclei of the cells were destroyed and many of them were starting to form large gold tubular structures.
All of his patients were vaccinated with Moderna’s mRNA COVID-19 vaccine. They all reported feeling extreme fatigue, dizziness, tiredness, a general aura of “not feeling well” and mental confusion.
Thick graphene fibers found in the blood of vaccinated individuals
Van Welbergen explained that the gold tube-like structures resemble the graphene oxide samples found by Spanish researchers. He described them as resembling “folded over toilet paper under paint.”
During another interview with the same media outlet, Van Welbergen presented images of his latest blood slides and explained what happened to the blood of his vaccinated patients.
In one image of a blood sample Van Welbergen shared, he pointed out that the vaccinated individual’s blood was coagulated, the red blood cells were badly misshapen and clumped together and the blood was filled with graphene fibers which dwarfed the red blood cells in size. He warned that graphene fibers these massive could block small blood vessels and cause serious health complications.
Van Welbergen also warned that he was starting to notice a magnetic or electric polarity effect on different sides of the graphene fibers. This behavior was not present when he first started examining the blood of his vaccinated patients, but they were now popping up out of nowhere.
“These things have changed,” he said. “Their reaction with surrounding blood cells has changed … and I don’t know what triggered it.”
The vaccinated are “shedding” and infecting the unvaccinated
Dr. Richard Fleming
DR. ANDREAS NOACK – Graphene Oxide Expert – Deceased November 2021 (shortly after this video presentation) – cause unknown
Synthesis and Toxicity of Graphene Oxide Nanoparticles: A Literature Review of In Vitro and In Vivo Studies
Graphene oxide (GO), an oxidized derivative of graphene, is currently used in biotechnology and medicine for cancer treatment, drug delivery, and cellular imaging. Also, GO is characterized by various physicochemical properties, including nanoscale size, high surface area, and electrical charge. However, the toxic effect of GO on living cells and organs is a limiting factor that limits its use in the medical field. Recently, numerous studies have evaluated the biocompatibility and toxicity of GO in vivo and in vitro. In general, the severity of this nanomaterial’s toxic effects varies according to the administration route, the dose to be administered, the method of GO synthesis, and its physicochemical properties.
Engaging in a straw man argument, the combined effects are ‘amplification’ so it doesn’t matter what the initial electrical current is, it’s amplified via graphene as a super conductor. We’re talking about amplification of current in cells, where the effects are clearly damaging.
Graphene Amplifies
The scientists used electromagnetic pulses from the TELBE facility with frequencies between 300 and 680 gigahertz and converted them in the graphene into electromagnetic pulses with three, five and seven times the initial frequency, i.e. up-converted them into the terahertz frequency range. “The nonlinear coefficients describing the efficiency of the generation of this third, fifth and seventh harmonic frequency were exceptionally high,” explains Turchinovich. “Graphene is thus possibly the electronic material with the strongest nonlinearity known to date. The good agreement of the measured values with our thermodynamic model suggests that we will also be able to use it to predict the properties of ultra high-speed nanoelectronic devices made of graphene.” Prof. Mischa Bonn, Director of the MPI-P, who was also involved in this work, emphasizes: “Our discovery is groundbreaking. We have demonstrated that carbon-based electronics can operate extremely efficiently at ultrafast rates. Ultrafast hybrid components made of graphene and traditional semiconductors are also conceivable.”
Graphene oxide induces toll-like receptor 4 (TLR4)-dependent necrosis in macrophages
2013
Graphene and graphene-based nanomaterials display novel and beneficial chemical, electrical, mechanical, and optical characteristics, which endow these nanomaterials with promising applications in a wide spectrum of areas such as electronics and biomedicine. However, its toxicity on health remains unknown and is of great concern. In the present study, we demonstrated that graphene oxide (GO) induced necrotic cell death to macrophages. This toxicity is mediated by activation of toll-like receptor 4 (TLR4) signaling and subsequently in part via autocrine TNF-α production. Inhibition of TLR4 signaling with a selective inhibitor prevented cell death nearly completely. Furthermore, TLR4-deficient bone marrow-derived macrophages were resistant to GO-triggered necrosis. Similarly, GO did not induce necrosis of HEK293T/TLR4-null cells. Macrophagic cell death upon GO treatment was partially attributed to RIP1-RIP3 complex-mediated programmed necrosis downstream of TNF-α induction. Additionally, upon uptake into macrophages, GO accumulated primarily in cytoplasm causing dramatic morphologic alterations and a significant reduction of the macrophagic ability in phagocytosis. However, macrophagic uptake of GO may not be required for induction of necrosis. GO exposure also caused a large increase of intracellular reactive oxygen species (ROS), which contributed to the cause of cell death. The combined data reveal that interaction of GO with TLR4 is the predominant molecular mechanism underlying GO-induced macrophagic necrosis; also, cytoskeletal damage and oxidative stress contribute to decreased viability and function of macrophages upon GO treatment.
The Molecular Influence of Graphene and Graphene Oxide on the Immune System Under In Vitro and In Vivo Conditions
2016
Graphene and graphene oxide (GO), due to their physicochemical properties and biocompatibility, can be used as an innovative biomedical material in biodetection, drug distribution in the body, treating neoplasms, regenerative medicine, and in implant surgery. Research on the biomedical use of graphene and GO that has been carried out until now is very promising and shows that carbon nanomaterials present high biocompatibility. However, the intolerance of the immune system to graphene nanomaterials, however low, may in consequence make it impossible to use them in medicine. This paper shows the specific mechanism of the molecular influence of graphene and GO on macrophages and lymphocytes under in vitro and in vivo conditions and their practical application in medicine. Under in vitro conditions graphene and GO cause an increased production of pro-inflammatory cytokines, mainly IL-1, IL-6, IL-10 and TNF-α, as a result of the activation of Toll-like receptors in macrophages. Graphene activates apoptosis in macrophages through the TGFbr/Smad/Bcl-2 pathway and also through JNK kinases that are stimulated by an increase of ROS in the cell or through a signal received by Smad proteins. Under in vivo conditions, graphene nanomaterials induce the development of the local inflammatory reaction and the development of granulomas in parenchymal organs.
Worldwide Insurance Companies And Investment Managers Spill And Count The Criminal Beans
Risks of graphene nanomaterial contamination in the soil: evaluation of major ions
The racket and ‘human experiment’ was formed to protect ‘the industry’ against the next worldwide chemical pollutant and while they were at it they decided to proceed with their favorite political agenda, communism (rid the sick, useless eaters, the stupid and those to whom they owe money), political control and protecting the bankers and the ‘underwriters’ from having to pay for the damage caused by ‘the industry’ as well as hide their usual criminal cartel activities and introduce their latest ‘tax’ scheme, ‘the carbon tax’ so they can keep up production of their latest ‘cash cow’ and get away with it.
No different than Rockefeller (the 13 family dynasties or oligarchs) making ‘medicine’ with petroleum products, taxing you for it, as they caused cancer and poured gasoline in to street as one of their first environmental disasters, preceded by a few and soon to be followed by many others as a result of the ‘industrial revolution’.
A. Baysal, H. Saygin & G. S. Ustabasi
Graphene: miracle material and potentially potent pollutant
2014
While the rest of the world has been harping on about how strong, conductive, light-sensitive and generally amazing graphene is, stern-faced researchers at the University of California have been investigating the material’s potential downsides. They’ve shown that graphene oxide nanoparticles fail to break apart easily in lakes and rivers, such that they can last a long time and travel large distances in water, potentially with serious consequences for the environment. As to what these consequences might be, exactly, nobody really knows — although there’s growing evidence that certain forms of graphene can be toxic, especially if they come into contact with the lungs.
Graphene slips deeper into lungs than predicted
2012
Researchers discover that once graphene enters the lungs the immune system has trouble getting rid of it
Graphene nanoplatelets can penetrate deeper into the lungs than their size would suggest, say UK researchers. And once there, the body’s natural defences cannot deal with them effectively. Chronic exposure could therefore lead to inflammation and disease in a similar way to asbestos fibres.
Commercial uses for graphene are already emerging, which means that it is going to be produced and handled in increasing amounts. As graphene is often supplied as a fine dust, Ken Donaldson and his team from the University of Edinburgh, UK, wanted to investigate the potential health risks of inhaling graphene particles.
Graphene’s negative environmental impacts
Researchers at the University of California, Riverside Bourns College of Engineering have found graphene oxide nanoparticles are very mobile in lakes or streams and likely to cause negative environmental impacts if released.
Graphene oxide* nanoparticles are an oxidized form of graphene, a single layer of carbon atoms prized for its strength, conductivity and flexibility. Applications for graphene include everything from cell phones and tablet computers to biomedical devices and solar panels.
The use of graphene and other carbon-based nanomaterials, such as carbon nanotubes, are growing rapidly. At the same time, recent studies have suggested graphene oxide may be toxic to humans.
Natural human enzyme can biodegrade graphene, scientists report
The enzyme, myeloperoxidase (MPO), is a peroxide enzyme released by neutrophils, cells found in the lungs that are responsible for the elimination of foreign bodies or bacteria that enter the body. If a foreign body or bacteria is detected inside of the body, neutrophils surround it and secrete MPO, thereby destroying the threat. Previous work by Graphene Flagship partners found MPO to biodegrade graphene oxide. However the structure of non-functionalized graphene was thought to be more degradation resistant. To test this, Bianco and his team looked at the effects of MPO, ex vivo, on two graphene forms: single- and few-layer.
Problem: In the present study, we demonstrated that graphene oxide (GO) induced necrotic cell death to macrophages….. (there are no neutrophils because graphene causes tolerance and it appears to cause neutropenia (low white cell count) caused by immune suppression and toxicity (similar to a chemo agent).
Neutrophils are one of five types of cell belonging to the white blood cell family, all of which are called leucocytes.
These include:
– neutrophils,
– lymphocytes,
– monocytes,
– eosinophils,
– and basophils.
All leukocytes serve in our body’s immunological and inflammatory responses, protecting us from irritants and malignant invaders.
– About 40%-60% of all white blood cells are neutrophils.
– Neutrophils, along with eosinophils and basophils, constitute a group of white blood cells known as granulocytes.
– Neutrophils are the most abundant type of white blood cell and the most abundant type of granulocytes.
Function:
Neutrophils are phagocytic; they engulf and digest other microorganisms.
SHEDDING, VACCINES AND GRAPHENE MACHINES BY DR. SAM BAILEY
Technically she is right, you don’t know how graphene was introduced but unless they initiated an aerosol campaign simultaneously to the injection schedule (and there is a patent trail suggesting at least some knew of many ways they could be ‘dispersed’ or ‘administered’), the fact that it is coinciding with the known injection schedule that has taken place and these patients weren’t showing up prior to that schedule or prior to 2021 (unless they got the flu shot or some other ‘graphene medical product’ and there are many) it is a pretty good indication THEY ARE SHEDDING GRAPHENES, especially after more injections. There are some pretty good indications ‘health care providers’ know this.
Anti-Flu vaccine 2019-2020 – VAXIGRIP – OPTICAL MICROSCOPE:
Alternavita: All you need to know (critical info in a nutshell)..... by focusing exclusively on these foundational health and immune development issues up to 90% of chronic conditions can be eliminated.
WHO STATEMENTS: 2017 Millennium Goal
- Breastfeeding,
- food (security)
- and water security (sanitation)
are major protective factors against malnutrition and critical factors in the maturation of healthy gut microbiota, characterized by a transient bifidobacterial bloom before a global rise in anaerobes. Early depletion in gut Bifidobacterium longum, a typical maternal probiotic, known to inhibit pathogens, represents the first step in gut microbiota alteration associated with severe acute malnutrition (SAM). Later, the absence of the Healthy Mature Anaerobic Gut Microbiota (HMAGM) leads to deficient energy harvest, vitamin biosynthesis and immune protection, and is associated with diarrhea, malabsorption and systemic invasion by microbial pathogens. A therapeutic diet and infection treatment may be unable to restore bifidobacteria and HMAGM.
Researchers found that malnourished children’s microbiota failed to follow the healthy pattern they identified in healthy children. The microbiota of malnourished children is immature, lagging in development behind that of their healthy peers. Supplementing these children’s meals with widely used therapeutic foods that increase calories and nutrient density reduces deaths from malnutrition, but it does not fix their persistent microbiota immaturity.
“Perhaps more insidious than slowing growth is malnutrition’s effect on less visible aspects of health, including impaired brain development and dysfunctional immunity, which follow these children throughout their lives”.
The Father of The Microbiome
Dr. Jeffrey Gordon
SIBO
SIBO can cause severe malabsorption, serious malnutrition and immune deficiency syndromes in children (non breastfed) and adults.
Prognosis is usually serious, determined mostly by the underlying disease that led to SIBO.
Immunizations
The WHO recommends that immunization or treatment be orally administered due to economic, logistical and security reasons. Furthermore, this route offers important advantages over systemic administration, such as reducing side effects, as the molecules are administered locally and have the ability to stimulate the GALT immune responses (Levine and Dougan, 1998; Neutra and Kozlowski, 2006; Bermúdez-Humarán et al., 2011).
Infections
For ANY infectious or parasitic disease to start, it is ALWAYS a requisite that the host suffer IMMUNODEFICIENCY. At the same time, infectious and parasitic diseases themselves cause additional IMMUNE SUPPRESSION and more MALNUTRITION. This immune suppression is SECONDARY to the accumulation of free radicals, especially oxidizing species, that occurs during and after infectious and parasitic diseases.
Clinical Aspects of Immunology and Biochem J.
Current IBD Research 2016
Currently available treatments for IBD, which target the systemic immune system, induce immunosuppression, thereby exposing the patient to the risk of infections and malignancy. The interplay between the gut and the systemic immune system determines the final effect on target organs, including the bowel mucosa. Inflammatory bowel diseases (IBD) are associated with an altered systemic immune response leading to inflammation-mediated damage to the gut and other organs.
Clinical & Translational Immunology (2016)
Gastroenterology and Liver Units, Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
Most importantly, the immune modulatory agents used today for IBD do not achieve remission in many patients.
Not all IBD patients benefit from currently available drugs. Young people with IBD do not want to be on long-term drug therapy. Oral immune therapy, while not yet studied in large cohorts of patients, may provide an answer to this unmet need.
Clinical & Translational Immunology (2016)
Gastroenterology and Liver Units, Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
Tolerance
Tolerance is the ability of the immune system to ‘see’ and respond appropriately. Without galactose (a necessary sugar) the immune system can not 'see'. Your immune system would not be able to function without galactose Your body wouldn’t know which cells are
“good” and what cells are “bad.” Your body wouldn’t know who the invaders were and which ones should be attacked by antibodies. As you will learn the importance of these ‘sugars’ in gut microbiota health is a rapidly expanding field of research, only recently
discovered, including HMO's (human milk oligosaccharides).
Why galactose?
Milk sugar aka lactose has been shown to be very beneficial for the human body though unlike sucrose, lactose is made up of glucose and galactose. There is no fructose in lactose. It is a healthy disaccharide sugar. Galactose is known as the “brain sugar” and supports brain development of babies and children. Galactose helps triggers long-term memory formation. Galactose has been shown to inhibit tumor growth and stop its spread, particularly to the liver. This beneficial sugar can also enhance wound healing, decrease inflammation, enhances cellular communication, and increases calcium absorption.
What does immune ‘tolerance’ mean in simple language?
Immune tolerance, or immunological tolerance, or immunotolerance, is a state of unresponsiveness of the immune system to
substances or tissue that have the capacity to elicit an immune response in a given organism. The Th1 cytokine profile is vital for clearance of certain organisms and ancillary immune activity, and a limiting effect on this cytokine profile may result in reduced chances for overcoming infections especially intra-cellular organisms residing within macrophages.
Effective clearance will depend on appropriate macrophage activation (which occurs through IFN≥ release by Th1 and NK cells) and production of nitric oxide. If this pathway is disrupted IFN≥ secretion is blocked, impairing macrophage activation.
Persistent blockade of these inhibitory receptors has lead to the breakdown in immune self tolerance, thereby increasing susceptibility to autoimmune or auto-inflammatory side effects, including rash, colitis, hepatitis and endocrinopathies.
Many drugs may cause checkpoint blockade toxicity including pharmaceutical drugs termed ‘immuno therapy’ by pharmaceutical companies, these include Mab drugs and cancer treatments.
Checkpoint Inhibitor–Induced Colitis: A New Type of Inflammatory Bowel Disease?
Madeline Bertha, MD MS, corresponding author1 Emanuelle Bellaguara, MD, Timothy Kuzel, MD, and Stephen Hanauer, MD
ACG Case Rep J. 2017; 4: e112.
Published online 2017 Oct 11. doi: 10.14309/crj.2017.112
PMCID: PMC5636906
PMID: 29043290
The Elderly
Mammal milk is required for enhanced phagocytosis as shown by research, especially in the elderly. Whole fat mammal milk can actually restore phagocytosis in senescent cells in the elderly. Phagocytosis, by which immune cells ‘eat’ bacteria or infected cells, is one of the mechanisms that help to resist infections. Lactic acid bacteria strains like acidophilus also increases phagocytosis.
Alternavita: All you need to know (critical info in a nutshell)..... by focusing exclusively on these foundational health and immune development issues up to 90% of chronic conditions can be eliminated.
WHO STATEMENTS: 2017 Millennium Goal
- Breastfeeding,
- food (security)
- and water security (sanitation)
are major protective factors against malnutrition and critical factors in the maturation of healthy gut microbiota, characterized by a transient bifidobacterial bloom before a global rise in anaerobes. Early depletion in gut Bifidobacterium longum, a typical maternal probiotic, known to inhibit pathogens, represents the first step in gut microbiota alteration associated with severe acute malnutrition (SAM). Later, the absence of the Healthy Mature Anaerobic Gut Microbiota (HMAGM) leads to deficient energy harvest, vitamin biosynthesis and immune protection, and is associated with diarrhea, malabsorption and systemic invasion by microbial pathogens. A therapeutic diet and infection treatment may be unable to restore bifidobacteria and HMAGM.
Researchers found that malnourished children’s microbiota failed to follow the healthy pattern they identified in healthy children. The microbiota of malnourished children is immature, lagging in development behind that of their healthy peers. Supplementing these children’s meals with widely used therapeutic foods that increase calories and nutrient density reduces deaths from malnutrition, but it does not fix their persistent microbiota immaturity.
“Perhaps more insidious than slowing growth is malnutrition’s effect on less visible aspects of health, including impaired brain development and dysfunctional immunity, which follow these children throughout their lives”.
The Father of The Microbiome
Dr. Jeffrey Gordon
SIBO
SIBO can cause severe malabsorption, serious malnutrition and immune deficiency syndromes in children (non breastfed) and adults.
Prognosis is usually serious, determined mostly by the underlying disease that led to SIBO.
Immunizations
The WHO recommends that immunization or treatment be orally administered due to economic, logistical and security reasons. Furthermore, this route offers important advantages over systemic administration, such as reducing side effects, as the molecules are administered locally and have the ability to stimulate the GALT immune responses (Levine and Dougan, 1998; Neutra and Kozlowski, 2006; Bermúdez-Humarán et al., 2011).
Infections
For ANY infectious or parasitic disease to start, it is ALWAYS a requisite that the host suffer IMMUNODEFICIENCY. At the same time, infectious and parasitic diseases themselves cause additional IMMUNE SUPPRESSION and more MALNUTRITION. This immune suppression is SECONDARY to the accumulation of free radicals, especially oxidizing species, that occurs during and after infectious and parasitic diseases.
Clinical Aspects of Immunology and Biochem J.
Current IBD Research 2016
Currently available treatments for IBD, which target the systemic immune system, induce immunosuppression, thereby exposing the patient to the risk of infections and malignancy. The interplay between the gut and the systemic immune system determines the final effect on target organs, including the bowel mucosa. Inflammatory bowel diseases (IBD) are associated with an altered systemic immune response leading to inflammation-mediated damage to the gut and other organs.
Clinical & Translational Immunology (2016)
Gastroenterology and Liver Units, Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
Most importantly, the immune modulatory agents used today for IBD do not achieve remission in many patients.
Not all IBD patients benefit from currently available drugs. Young people with IBD do not want to be on long-term drug therapy. Oral immune therapy, while not yet studied in large cohorts of patients, may provide an answer to this unmet need.
Clinical & Translational Immunology (2016)
Gastroenterology and Liver Units, Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
Tolerance
Tolerance is the ability of the immune system to ‘see’ and respond appropriately. Without galactose (a necessary sugar) the immune system can not 'see'. Your immune system would not be able to function without galactose Your body wouldn’t know which cells are
“good” and what cells are “bad.” Your body wouldn’t know who the invaders were and which ones should be attacked by antibodies. As you will learn the importance of these ‘sugars’ in gut microbiota health is a rapidly expanding field of research, only recently
discovered, including HMO's (human milk oligosaccharides).
Why galactose?
Milk sugar aka lactose has been shown to be very beneficial for the human body though unlike sucrose, lactose is made up of glucose and galactose. There is no fructose in lactose. It is a healthy disaccharide sugar. Galactose is known as the “brain sugar” and supports brain development of babies and children. Galactose helps triggers long-term memory formation. Galactose has been shown to inhibit tumor growth and stop its spread, particularly to the liver. This beneficial sugar can also enhance wound healing, decrease inflammation, enhances cellular communication, and increases calcium absorption.
What does immune ‘tolerance’ mean in simple language?
Immune tolerance, or immunological tolerance, or immunotolerance, is a state of unresponsiveness of the immune system to
substances or tissue that have the capacity to elicit an immune response in a given organism. The Th1 cytokine profile is vital for clearance of certain organisms and ancillary immune activity, and a limiting effect on this cytokine profile may result in reduced chances for overcoming infections especially intra-cellular organisms residing within macrophages.
Effective clearance will depend on appropriate macrophage activation (which occurs through IFN≥ release by Th1 and NK cells) and production of nitric oxide. If this pathway is disrupted IFN≥ secretion is blocked, impairing macrophage activation.
Persistent blockade of these inhibitory receptors has lead to the breakdown in immune self tolerance, thereby increasing susceptibility to autoimmune or auto-inflammatory side effects, including rash, colitis, hepatitis and endocrinopathies.
Many drugs may cause checkpoint blockade toxicity including pharmaceutical drugs termed ‘immuno therapy’ by pharmaceutical companies, these include Mab drugs and cancer treatments.
Checkpoint Inhibitor–Induced Colitis: A New Type of Inflammatory Bowel Disease?
Madeline Bertha, MD MS, corresponding author1 Emanuelle Bellaguara, MD, Timothy Kuzel, MD, and Stephen Hanauer, MD
ACG Case Rep J. 2017; 4: e112.
Published online 2017 Oct 11. doi: 10.14309/crj.2017.112
PMCID: PMC5636906
PMID: 29043290
The Elderly
Mammal milk is required for enhanced phagocytosis as shown by research, especially in the elderly. Whole fat mammal milk can actually restore phagocytosis in senescent cells in the elderly. Phagocytosis, by which immune cells ‘eat’ bacteria or infected cells, is one of the mechanisms that help to resist infections. Lactic acid bacteria strains like acidophilus also increases phagocytosis.