Baking Soda And Inflammation Research
can activate anti inflammatory pathways in key organs
Baking Soda
Recent research has uncovered that consuming sodium bicarbonate (NaHCO₃), commonly known as baking soda, can activate an anti-inflammatory pathway in the spleen. This discovery suggests that NaHCO₃ might help reduce inflammation associated with various diseases.
Understanding Inflammation and the Immune System
Inflammation is the body’s natural response to injury or infection, involving immune cells like macrophages that work to eliminate harmful agents and initiate healing. However, chronic inflammation can lead to tissue damage and is linked to diseases such as chronic kidney disease (CKD). Macrophages can exist in different states: M1 macrophages promote inflammation, while M2 macrophages help reduce it. Balancing these states is crucial for maintaining health.
The Role of Sodium Bicarbonate
Sodium bicarbonate is an alkaline substance that neutralizes acids. It’s often used to treat conditions like heartburn. Researchers have found that when ingested, NaHCO₃ can shift macrophages from the inflammatory M1 state to the anti-inflammatory M2 state. This shift has been observed in the spleen, blood, and kidneys of rats, as well as in the blood of human subjects after consuming NaHCO.
The Spleen’s Role in Immune Regulation
The spleen is an organ that filters blood and plays a key role in immune responses. It contains various immune cells, including macrophages and T-lymphocytes, which help regulate inflammation. The study found that after NaHCO₃ ingestion, there was an increase in regulatory T-lymphocytes (FOXP3+CD4+ T cells) in the spleen, blood, and kidneys of rats. These cells are known to suppress inflammatory responses, contributing to the anti-inflammatory effect.
Mesothelial Cells as Signal Transmitters
Mesothelial cells line body cavities and cover organs like the spleen. The study provided evidence that these cells might transmit signals from the vagus nerve to the spleen, promoting an anti-inflammatory response. Disrupting the connections between mesothelial cells and the spleen or cutting the vagus nerve reduced the anti-inflammatory effects of NaHCO₃, highlighting the importance of this pathway.
Implications for Treating Inflammatory Diseases
These findings suggest that oral NaHCO₃ could be a simple, cost-effective way to activate the body’s anti-inflammatory pathways, potentially benefiting patients with inflammatory conditions like CKD. By promoting the shift of macrophages to the M2 state and increasing regulatory T cells, NaHCO₃ may help reduce chronic inflammation and its associated risks.
Considerations and Future Research
While the results are promising, more research is needed to fully understand the mechanisms and to determine the appropriate dosages for therapeutic use. It’s also important to consider that excessive intake of sodium bicarbonate can lead to side effects, and individuals should consult healthcare professionals before starting any new treatment.
In Summary
In summary, the study indicates that consuming sodium bicarbonate can activate a splenic anti-inflammatory pathway, with mesothelial cells playing a crucial role in transmitting signals that promote this response. This discovery opens new avenues for potential treatments of inflammatory diseases through dietary interventions.
PubMed Central
How To Use Baking Soda
Baking soda can be a simple and inexpensive way to support health, but it’s important to use it carefully. Julie Hand, a holistic health and nutrition counselor, suggests starting with one-eighth of a teaspoon mixed into a regular glass of water. Over time, you can gradually increase the amount to one-fourth of a teaspoon.
If you feel short of breath or notice your heart racing after drinking the mixture, it’s a sign you may have taken too much. People at risk of a condition called alkalosis, where the body’s pH becomes too alkaline, should avoid using baking soda this way.
Baking soda might help reduce inflammation and could even be helpful for autoimmune diseases like rheumatoid arthritis (RA). However, it’s always important to talk to your doctor before trying it as a treatment.
Baking soda has other uses too. It’s commonly used to ease acid reflux and has even been studied as a potential way to prevent certain cancers. Michelle Neilly, a nutrition coach, notes that while there’s no miracle cure, remedies like baking soda and apple cider vinegar have been trusted for generations. For people with RA, it could provide a natural way to reduce inflammation.
A true bio active – Immune For Life
Bovine colostrum contains leukocytes, which are cells that may be important for passive immunity. The types of leukocytes in colostrum include:
Macrophages: The most common cell type, making up 50–90% of colostrum leukocytes.
T-lymphocytes: The second most common cell type, making up about 16% of colostrum leukocytes.
B-lymphocytes: A small number of B-lymphocytes are present, usually less than 5%.
Polymorphonuclear cells: Mostly neutrophils, these cells make up 3–6% of colostrum leukocytes.
Epithelial cells: These cells make up 2–15% of colostrum leukocytes.
The number of leukocytes in colostrum can vary depending on the cow’s age, breed, health, and immune status.
Colostrum also contains other bioactive components, such as immunoglobulins, growth factors, vitamins, and hormones.
Source:
PubMed Central
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Immune For Life
Reintroduce yourself to nature’s prescription for health and natural oral immune therapeutics that modulate the gut and systemic biology by using products that are the bio active backbone of immunity. Release the power of activating factors that have transformed the health outcomes of thousands. These and other natural oral immune therapeutics that are beginning to flood the marketplace are promising to shape the future of medicine as safe bio actives for future health products and minimally refined functional foods, including infant formula.Learn how you can quickly begin to transform your gut and immune health today without complicated diets or expensive plans, no matter your age!
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Immune For Life
Reintroduce yourself to nature’s prescription for health and natural oral immune therapeutics that modulate the gut and systemic biology by using products that are the bio active backbone of immunity. Release the power of activating factors that have transformed the health outcomes of thousands. These and other natural oral immune therapeutics that are beginning to flood the marketplace are promising to shape the future of medicine as safe bio actives for future health products and minimally refined functional foods, including infant formula.Learn how you can quickly begin to transform your gut and immune health today without complicated diets or expensive plans, no matter your age!
five minute candied walnuts
Quell sugar cravings in a hurry with this quick and easy recipe. Minimally chop in a food processor for a yogurt topping, add to a fruit or green salad or just keep a jar for a snack. A small serving keeps sugar grams within healthy range.
Estimated Nutritional Information per Serving:
4 servings, each serving would contain:
* Calories: Approximately 200-220 kcal
* Total Fat: Around 18-20 grams
* Saturated Fat: About 2-3 grams
* Cholesterol: Approximately 5-7 milligrams
* Sodium: Around 1-2 milligrams
* Total Carbohydrates: About 10-12 grams
* Dietary Fiber: Approximately 2 grams
* Sugars: Around 8-10 grams
* Protein: About 4-5 grams
protect metabolic health
Remember, no more than 6 teaspoons (25 grams) of added sugar per day for women and 9 teaspoons (38 grams) for men. The AHA limits for children vary depending on their age and caloric needs, but range between 3-6 teaspoons (12 – 25 grams) per day. Children under two should have zero grams of sugar per day.
Source:
PubMed Central